The anti debris plate of fuel assembly for the PWR is a precision machined part,which requires high dimensional accuracy and mechanical properties. At present,the anti debris plate adopts the EDM technology,which needs to process thousands of special-shaped square holes on the 210 mm square thin plate. The machining cycle of a single part is long and the efficiency is low. In order to meet the demand of mass production of new nuclear fuel,it is necessary to study the advanced laser manufacturing technology in the world and find a new processing method that takes both quality and efficiency into account. From the perspectives of raw material preparation,manufacturing process and post-processing methods,the project studies the application of advanced laser SLM manufacturing technology in the processing of the anti debris plate of fuel assembly. The research results are of great significance to solve the technical problems of autonomous nuclear fuel assembly manufacturing and improve the technological level of fuel assembly manufacturing technology.