Cladding a thin and uniform layer of Inconel625 nickel-based alloy onto the heat-exchanger panels for high-temperature corrosion resistance purpose could effectively extend the service life of a refuse incinerator,and is proved to be a feasible and reliable solution with the best cost perfor-mance ratio. Conventional arc cladding technology could do this surface modification job but it has some disadvantages such as high substrate dilution,low deposition efficiency and the workpieces should be welded vertically. In this paper,a hot-wire laser cladding system is described,witch adopts a high power diode laser generator with a specific wavelength and homogeneous energy density and a 35 kHz ultrahigh frequency pulsed low voltage hot-wire laser power supply,and successfully clads the Inconel 625 onto a wall surface placed horizontally by gantry type welding tractor. The experiment shows that the dilution rate of the cladding layer is less than5%,while the efficiency of cladding is about 8.8 kg/h. This innovative system can significantly improve the quality of the cladding layer and the productivity,simplify workpiece installation procedures,reduce labor costs and avoid potential safety hazards.