For welding control rod guide tube 304 stainless steel for nuclear power,the " ○ "-shaped laser scanning welding,the " | "-shaped laser scanning welding and the "8"-shaped laser scanning welding methods were used to compare with the conventional laser welding. The influence of the main welding parameters such as scanning amplitude and scanning frequency on the appearance of weld and the welding pores were analyzed,in addition,a comprehensive quality evaluation was performed on the butt joints of the 7 mm thick guide cylinder simulation. The results show that the three laser scanning welding methods are superior to the conventional laser welding in the aspects of the appearance of weld and the welding pore,and there are differences in the inhibition degree of welding pores by different spot scanning paths,in general,the "○"-shaped laser scanning welding is the best. If want the laser scanning welding takes effect to inhibit the welding pores,the scanning amplitude and scanning frequency need to reach the threshold,and when exceeding the threshold,increasing the scanning amplitude or frequency properly can enhance the effect of inhibiting pores. When the scanning amplitude is 2 mm and the scanning frequency is 50 Hz,there is no welding pore in weld. The welded joint has a good corrosion resistance,and the deformation can be controlled within 0.3 mm.