Based on the groove type and dimension of pipeline BOSS weld in nuclear power plant,and the non-destructive testing scheme of BOSS weld in manufacturing and installation stage,the main causes of defects types and weld failures are analyzed. Taking the BOSS weld of main pipeline as an example,aiming at the main characteristics of weld structure and dimension,the key points of radiographic technology,film sensitivity and limitation of BOSS weld are studied and verified,which provides reference for the radiographic detection scheme of pipeline BOSS weld in nuclear power plant.