As a new degradable biological material,magnesium alloy has important application value in the field of the fourth generation of vascular stent implantation products,but its application and promotion are restricted due to the difficulty in the processing of micro-tubes. A new method of electro-explosive spray deposition of magnesium alloy micro tube is proposed and the process is studied. The results show that when the wire diameter is 0.5 mm, the initial voltage is 14 k V, and the deposition distance is 25 mm, the uniformity,compactness and integrity of the deposition layer are good, and the nanocrystalline structure is obtained. The magnesium alloy micro tube with an outer diameter of 3.5 mm and a wall thickness of 0.12 mm are prepared, which meet the size requirements of the magnesium alloy vascular stent.