The materials surface morphologies were observed by using scanning electron microscope（SEM）. The surface roughness and hydrophobicity,laser-MIG hybrid welding penetration depth were investigated after laser cleaning. The results indicate that the materials surface morphology,surface roughness and hydrophobicity are different with various laser cleaning parameters. Compared to the as-received and mechanically polished samples,while the laser scanning speed less than 100 mm/s,the surface roughness of aluminum alloy increased with the increase of scanning speed. The laser-arc hybrid welding qualities were improved to some extent.The maximum penetration depth was 3.374 mm while the laser scanning speed was 50 mm/s. Compared to the as-received and mechanically polished samples,the weld penetration depth increased by 23.4% and 10.1%,respectively.